One hit wonder: single dose azithromycin could eliminate trachoma

Abstract

Trachoma, caused by the bacterium Chlamydia trachomatis, is the most common infectious cause of blindness. To prevent trachoma blindness, health programmes in Tanzania and elsewhere currently offer an annual dose of the antibiotic azithromycin to everyone in areas where at least 20 percent of children have active disease. Is this the most effective and efficient dosing strategy?